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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3955 | AR7 | Retinoid Receptor | |
AR7 is a retinoic acid receptor α (RARα) antagonist. | |||
T7894 | Tazarotenic acid | AGN-190299 | Others |
Tazarotenic acid (AGN-190299) is a retinoid prodrug which is converted to its active form | |||
T14912 | CD3254 | Retinoid Receptor | |
CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation. | |||
T9635 | Cedirogant | ABBV-157 | ROR |
Cedirogant (ABBV-157) is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study. | |||
T23383 | SR11237 | SR 11237 | Others , RAR/RXR |
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | |||
T7388 | GSK805 | ROR | |
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi... | |||
T11844 | LG-100064 | Retinoid Receptor , Autophagy | |
LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ) | |||
T17209 | UVI 3003 | Retinoid Receptor , Autophagy | |
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively). | |||
T22843 | HX 531 | Retinoid Receptor | |
RXR antagonist | |||
T11303 | Fluorobexarotene | Retinoid Receptor | |
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RX... | |||
TP1313L | Cecropin B acetate | Cecropin B acetate(80451-05-4 Free base) | P450 , Retinoid Receptor , Parasite |
Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences. Cecropin B acetate exhibits strong antimicrobial a... | |||
TN6735 | Bigelovin | Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR | |
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote... | |||
T77499 | MSU-42011 | NOS , Retinoid Receptor , NO Synthase , PERK , Lipid | |
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist.MSU-42011 potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level.MSU-42011 has demonstrated anti... | |||
T25472 | GW0791 | GW 0791,GW-0791 | |
GW0791 is a retinoid X receptor α (RXRα) agonist. | |||
T23665 | AGN 191701 | AGN-191701,AGN191701 | |
AGN 191701 is an agonist of the Retinoid X receptor. | |||
T29720 | Agn 190727 | Agn-190727,Agn190727 | |
Agn 190727 is a retonoic acid receptor that can induce retinoid-induced hypertriglyceridemia. | |||
T70440 | AGN-191659 | ||
AGN-191659 is a Retinoid X Receptor (RXR) pan-agonist. RXR pan-agonists have been shown to modulate endothelial cell proliferation. | |||
T69695 | Izumerogant | ||
Izumerogant is an inverse agonist of the retinoid-related orphan receptor-gamma (RORγ). | |||
T10246 | Adapalene sodium salt | CD 271 sodium salt | Others |
Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist. | |||
T24857 | TBTC | ||
TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer's disease model mice. |